Publications

Steensels S, Qiao J, Zhang Y, Maner-Smith KM, Kika N, Holman CD, Corey KE, W Bracken C, Ortlund EA, Ersoy BA.  2020.  Acyl-Coenzyme A Thioesterase 9 Traffics Mitochondrial Short-Chain Fatty Acids Toward De Novo Lipogenesis and Glucose Production in the Liver.. Hepatology. 72(3):857-872.

Steensels S, Qiao J, Ersoy BA.  2020.  Transcriptional Regulation in Non-Alcoholic Fatty Liver Disease.. Metabolites. 10(7)

Steensels S, Ersoy BA.  2018.  Fatty acid activation in thermogenic adipose tissue.. Biochim Biophys Acta.

Siljee JE, Wang Y, Bernard AA, Ersoy BA, Zhang S, Marley A, Von Zastrow M, Reiter JF, Vaisse C.  2018.  Subcellular localization of MC4R with ADCY3 at neuronal primary cilia underlies a common pathway for genetic predisposition to obesity.. Nat Genet. 50(2):180-185.

Ersoy BA, Maner-Smith KM, Li Y, Alpertunga I, Cohen DE.  2018.  Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress.. J Clin Invest. 128(1):141-156.

Kawano Y, Ersoy BA, Li Y, Nishiumi S, Yoshida M, Cohen DE.  2014.  Thioesterase superfamily member 2 (Them2) and phosphatidylcholine transfer protein (PC-TP) interact to promote fatty acid oxidation and control glucose utilization.. Mol Cell Biol. 34(13):2396-408.

Ersoy BA, Tarun A, D'Aquino K, Hancer NJ, Ukomadu C, White MF, Michel T, Manning BD, Cohen DE.  2013.  Phosphatidylcholine transfer protein interacts with thioesterase superfamily member 2 to attenuate insulin signaling.. Sci Signal. 6(286):ra64.

Ersoy BA, Pardo L, Zhang S, Thompson DA, Millhauser G, Govaerts C, Vaisse C.  2012.  Mechanism of N-terminal modulation of activity at the melanocortin-4 receptor GPCR.. Nat Chem Biol. 8(8):725-30.

Aslan IR, Ranadive SA, Ersoy BA, Rogers SJ, Lustig RH, Vaisse C.  2011.  Bariatric surgery in a patient with complete MC4R deficiency.. Int J Obes (Lond). 35(3):457-61.

Shishova EY, Stoll JM, Ersoy BA, Shrestha S, Scapa EF, Li Y, Niepel MW, Su Y, Jelicks LA, Stahl GL et al..  2011.  Genetic ablation or chemical inhibition of phosphatidylcholine transfer protein attenuates diet-induced hepatic glucose production.. Hepatology. 54(2):664-74.

Calton MA, Ersoy BA, Zhang S, Kane JP, Malloy MJ, Pullinger CR, Bromberg Y, Pennacchio LA, Dent R, McPherson R et al..  2009.  Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study.. Hum Mol Genet. 18(6):1140-7.

Ranadive SA, Ersoy B, Favre H, Cheung CC, Rosenthal SM, Miller WL, Vaisse C.  2009.  Identification, characterization and rescue of a novel vasopressin-2 receptor mutation causing nephrogenic diabetes insipidus.. Clin Endocrinol (Oxf). 71(3):388-93.

Dubern B, Lubrano-Berthelier C, Mencarelli M, Ersoy B, Frelut M-L, Bouglé D, Costes B, Simon C, Tounian P, Vaisse C et al..  2008.  Mutational analysis of the pro-opiomelanocortin gene in French obese children led to the identification of a novel deleterious heterozygous mutation located in the alpha-melanocyte stimulating hormone domain.. Pediatr Res. 63(2):211-6.

Ahituv N, Kavaslar N, Schackwitz W, Ustaszewska A, Martin J, Hebert S, Doelle H, Ersoy B, Kryukov G, Schmidt S et al..  2007.  Medical sequencing at the extremes of human body mass.. Am J Hum Genet. 80(4):779-91.

Lucas LH, Ersoy BA, Kueltzo LA, Joshi SB, Brandau DT, Thyagarajapuram N, Peek LJ, C Middaugh R.  2006.  Probing protein structure and dynamics by second-derivative ultraviolet absorption analysis of cation-{pi} interactions.. Protein Sci. 15(10):2228-43.

Kueltzo LA, Ersoy B, Ralston JP, C Middaugh R.  2003.  Derivative absorbance spectroscopy and protein phase diagrams as tools for comprehensive protein characterization: a bGCSF case study.. J Pharm Sci. 92(9):1805-20.

Kueltzo LA, Osiecki J, Barker J, Picking WL, Ersoy B, Picking WD, C Middaugh R.  2003.  Structure-function analysis of invasion plasmid antigen C (IpaC) from Shigella flexneri.. J Biol Chem. 278(5):2792-8.